Myohemerytherin is a globular protein that binds molecular oxygen and is used by invertebrates to provide oxygen to metabolizing tissues. Objectives of this exercise are to develop an understanding of the structure of globular proteins which includes these aspects: the nature of the tertiary structure, the role that secondary structural components have in the tertiary structure and the important forces that maintain the tertiary structure. In addition, develop an understanding of how molecular oxygen binds to the protein.

Chapter 1

Tertiary structure is over viewed, and the secondary structural components are highlighted.

Chapter 2

Buried and surface residues are identified as to their type, and some of the side chain interactions that maintain the tertiary structure are illustrated.

Chapter 3

Structure of O₂ binding center is featured .

1.  Biological Source: retractor muscle of sipunculan worm; Reference: S.Sheriff, W.A.Hendrickson, J.L. Smith "Structure of Myohemerythrin in the AzidoMet State at 1.7/1.3 Angstroms Resolution" J.Mol.Biol V. 197, 273, 1987

This is a Presentation in Protein Explorer (PiPE) prepared with proteinexplorer.org. Development of Protein Explorer was supported by a grant to Eric Martz from the Division of Undergraduate Education of the US National Science Foundation.